Age-standardized attributes off 86,149 feamales in the brand new NHS I within the 1994 and you will 94,715 women in the fresh new NHS II inside the 1995 from the quintiles out-of magnesium, potassium, and you may calcium intakes 1
Model dos is actually modified for model step 1 as well as for intakes out of potassium and you will calcium supplements (quintiles out of grams/d)
From the multivariate analyses, full and you can losing weight magnesium consumption was basically inversely associated with the danger of complete but ischemic or hemorrhagic heart attack ( Dining table 2). The brand new pooled multivariate RR for full heart attack was 0.87 (95% CI: 0.78, 0.97; P-trend = 0.07) into review of females throughout the highest which have lowest quintiles away from full magnesium intake; while new pooled multivariate RR to your review out-of highest having lower quintiles regarding fat reduction magnesium intake are 0.81 (95% CI: 0.69, 0.94; P-trend = 0.001) to own overall stroke. Overall potassium consumption is actually inversely of this danger of overall but maybe not ischemic otherwise hemorrhagic stroke ( Dining table step 3). To own assessment of women about large having low quintiles off complete potassium intake, this new pooled multivariate RR for overall stroke is actually 0.89 (95% CI: 0.80, 0.99; P-pattern = 0.01). Multivariate RRs both for magnesium and potassium was basically attenuated when the step three nutritional elements was in fact as part of the models on top of that (multivariate model dos). You will find 
no significant relationship between full or dieting calcium intake and you will overall, ischemic, otherwise hemorrhagic coronary attack ( Desk cuatro). Multivariate RRs getting complete magnesium (Extra Table step 1), total potassium (Extra Dining table 2), complete calcium (Extra Desk 3), fat loss magnesium (Supplemental Dining table cuatro), dieting potassium (Extra Table 5), and you will weightloss calcium supplements (Supplemental Table 6) and danger of full, ischemic, and you may hemorrhagic shots for each and every cohort alone receive regarding the extra issue.
Pooled RRs (95% CIs) out of overall, ischemic, and you can hemorrhagic shots by the quintiles regarding overall and you may diet magnesium consumption when you look at the 86,149 ladies in new NHS I and you can 94,715 ladies in the NHS II step one
Values are the n of cases. Cox proportional hazards models were used to estimate RRs and 95% CIs. Model 1 was adjusted for age, calendar year, total calories (quintiles of kcal), BMI (in kg/m 2 ; <25, 25 to <30, or ?30), parental history of heart disease (aged ?60 y), alcohol intake (0, 0 to <5, 5 to <10, 10 to <15, or ?15 g/d), physical activity (<3, 3 to <9, 9 to<18, 18 to <27, or ?27 metabolic equivalent tasks/wk), smoking, postmenopausal hormone therapy, oral contraceptive use (never, past, or current), menopausal status (premenopausal or postmenopausal), aspirin (0 to <2 or ?2 pills/wk), multivitamin, history of hypertension, hypercholesterolemia, diabetes at baseline, and thiazide use (yes or no). NHS, Nurses' Health Study.
Pooled RRs (95% CIs) away from complete, ischemic, and hemorrhagic strokes of the quintiles from overall and fat loss magnesium intake within the 86,149 feamales in the fresh NHS We and you can 94,715 women in the fresh NHS II 1
Values are the n of cases. Cox proportional hazards models were used to estimate RRs and 95% CIs. Model 1 was adjusted for age, calendar year, total calories (quintiles of kcal), BMI (in kg/m 2 ; <25, 25 to <30, or ?30), parental history of heart disease (aged ?60 y), alcohol intake (0, 0 to <5, 5 to <10, 10 to <15, or ?15 g/d), physical activity (<3, 3 to <9, 9 to<18, 18 to <27, or ?27 metabolic equivalent tasks/wk), smoking, postmenopausal hormone therapy, oral contraceptive use (never, past, or current), menopausal status (premenopausal or postmenopausal), aspirin (0 to <2 or ?2 pills/wk), multivitamin, history of hypertension, hypercholesterolemia, diabetes at baseline, and thiazide use (yes or no). NHS, Nurses' Health Study.
